SPRO Technical

Technical Sentiment Analysis for Spero Therapeutics Inc (SPRO) As of 2026-03-04, Spero Therapeutics Inc (SPRO) is exhibiting a Buy technical sentiment. Our proprietary analysis, which aggregates 12 technical signals, shows that 7 indicators are flashing buy, while 5 are indicating sell.

Momentum Indicators: RSI, MACD & Overbought/Oversold Status Currently, the Relative Strength Index (RSI) for SPRO stands at 49.865, which suggests a Neutral condition. Meanwhile, the MACD (12, 26) indicator is at -0.0369, providing a Sell signal for short-term momentum. Other oscillators like the Stochastic Oscillator at 33.906 and the Commodity Channel Index (CCI) at -30.793 further confirm a -0.04 outlook for the stock.

Support, Resistance & Moving Averages From a structural perspective, SPRO is trading above its 60-day moving average of $2.34 and above its 200-day long-term moving average of $2.281. Key price levels to watch include the immediate resistance at $2.399 and strong support at $2.099. A break above $2.399 could signal a bull continuation, while falling below $2.099 may test the next Fibonacci floor at $1.955.