Acadia Pharma to Announce Q4 Earnings on February 25
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 6 days ago
0mins
Should l Buy ACAD?
Source: seekingalpha
- Earnings Announcement Date: Acadia Pharma is set to announce its Q4 2023 earnings on February 25 after market close, with market participants keenly awaiting the results, which may impact stock performance.
- Earnings Expectations: The consensus EPS estimate stands at $0.14, indicating a year-over-year growth expectation that reflects investor optimism regarding the company's profitability.
- Revenue Estimate Fluctuations: Revenue is projected at $292.59 million, representing a 12.7% increase year-over-year; however, in the last three months, revenue estimates have seen three upward revisions and five downward revisions, indicating market uncertainty about future performance.
- Analyst Rating Changes: Over the past three months, EPS estimates have experienced two upward revisions and four downward revisions, suggesting a divergence in analyst opinions regarding Acadia Pharma's earnings outlook, which could influence investor confidence.
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Analyst Views on ACAD
Wall Street analysts forecast ACAD stock price to rise
12 Analyst Rating
7 Buy
5 Hold
0 Sell
Moderate Buy
Current: 24.560
Low
23.00
Averages
31.17
High
40.00
Current: 24.560
Low
23.00
Averages
31.17
High
40.00
About ACAD
Acadia Pharmaceuticals Inc. is a biopharmaceutical company. It develops and commercializes medicines that address unmet medical needs in central nervous system (CNS) disorders and rare diseases. It has a portfolio of product candidates and research programs that are designed to address significant unmet medical needs in CNS disorders and rare diseases. Its pipeline includes NUPLAZID (pimavanserin), DAYBUE (trofinetide), ACP-101, ACP-204, and ACP-711. NUPLAZID is a selective serotonin inverse agonist/antagonist preferentially targeting the 5-HT2A receptor. NUPLAZID is developed for the treatment for Parkinson's Disease Psychosis. Trofinetide is a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 designed to treat the core symptoms of Rett syndrome by reducing neuroinflammation and supporting synaptic function. Its early-stage research programs and product candidates include ACP-211, ACP-2591, ACP-271, and Antisense Oligonucleotide (ASO) Programs.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Re-examination Request: Acadia Pharmaceuticals will request a re-examination of the CHMP's opinion on trofinetide, aimed at treating Rett syndrome in patients aged two and older, reflecting ongoing commitment to drug approval efforts.
- Market Authorization: Trofinetide is already approved in the U.S., Canada, and Israel, representing the first and only treatment for Rett syndrome, highlighting its potential and significance in the global market.
- Executive Commentary: Acadia CEO Catherine Owen Adams expressed disappointment over the CHMP's refusal but remains optimistic about the drug's meaningful benefits for Rett syndrome patients, emphasizing positive feedback from patients and clinicians.
- Market Reaction: ACAD shares fell 7.13% to $22.81 during regular trading on Monday, yet gained 0.04% in after-hours trading, indicating cautious optimism in the market regarding the drug's future potential.
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- Trial Pause Reason: Aardvark Therapeutics announced a voluntary pause of its ARD-101 trial for Prader-Willi Syndrome due to cardiac observations in a healthy volunteer study, with data release now expected to be delayed until Q3 2026, potentially impacting the company's future R&D trajectory.
- Severe Market Reaction: Following the trial pause announcement, Aardvark's shares plunged 53% in after-hours trading, reflecting extreme investor concern over the company's outlook, which may lead to financing challenges and diminished market confidence.
- Competitor Dynamics: In contrast, Soleno Therapeutics' VYKAT XR has become the first FDA-approved treatment for hyperphagia in Prader-Willi Syndrome, despite facing short-selling pressure and safety concerns from Scorpion Capital, highlighting the intense competition in the market.
- Industry-Wide Challenges: Against the backdrop of Aardvark's trial pause, Acadia Pharmaceuticals also halted development of its intranasal Carbetocin, indicating that the challenges and risks associated with successful R&D in the Prader-Willi Syndrome treatment space are increasing, which could affect the overall investment attractiveness of the sector.
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- Significant Revenue Growth: ACADIA Pharmaceuticals reported adjusted total revenues of $298 million in Q4 2025, a 16% increase year-over-year, with annual revenues surpassing $1 billion for the first time at $1.08 billion, indicating strong commercial execution in the NUPLAZID and DAYBUE brands.
- Optimistic NUPLAZID Sales Outlook: The company expects NUPLAZID net sales to reach between $760 million and $790 million in 2026, representing a growth of 10% to 14% over 2025, laying a solid foundation for achieving blockbuster status with $1 billion in sales by 2028.
- DAYBUE Market Expansion: DAYBUE's net sales were reported at $110 million for Q4 and $391 million for the year, successfully expanding into the U.S. community physician market, with 76% of new prescriptions originating from community-based physicians, reflecting the company's success in broadening its market reach.
- R&D and Financial Outlook: Projected R&D expenses for 2026 are between $385 million and $410 million, with SG&A expenses expected to be between $660 million and $700 million, reflecting ongoing investments in foundational capabilities and field force expansion to support future growth potential.
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- Earnings Announcement Date: Acadia Pharma is set to announce its Q4 2023 earnings on February 25 after market close, with market participants keenly awaiting the results, which may impact stock performance.
- Earnings Expectations: The consensus EPS estimate stands at $0.14, indicating a year-over-year growth expectation that reflects investor optimism regarding the company's profitability.
- Revenue Estimate Fluctuations: Revenue is projected at $292.59 million, representing a 12.7% increase year-over-year; however, in the last three months, revenue estimates have seen three upward revisions and five downward revisions, indicating market uncertainty about future performance.
- Analyst Rating Changes: Over the past three months, EPS estimates have experienced two upward revisions and four downward revisions, suggesting a divergence in analyst opinions regarding Acadia Pharma's earnings outlook, which could influence investor confidence.
See More
- Stake Increase: Baker Bros. Advisors reported a purchase of 2,005,813 shares of Kymera Therapeutics in its February 17, 2026 SEC filing, representing an estimated trade value of $135.45 million, indicating strong confidence in the company.
- Market Value Growth: The fund's quarter-end position in Kymera Therapeutics increased by $297.15 million due to this purchase, reflecting the dual impact of trading activity and share price appreciation, further solidifying its market position.
- Stock Performance: As of February 17, 2026, Kymera's shares were priced at $84.84, marking a 130% increase over the past year, significantly outperforming the S&P 500 by 118.13 percentage points, showcasing its robust performance in the biotech sector.
- R&D Outlook: With approximately $1.6 billion in cash at the beginning of 2026, Kymera supports its leading oral immunology pipeline, which is expected to drive sustained growth for the company in the coming years.
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